UTC−3
| 07:00 | Chaves – AVS | 2–2 |
| 10:00 | FC Penafiel – Sporting CP B | 2–0 |
| 12:30 | CA Bizertin – AS Marsa | 1–0 |
| 12:30 | Esperance ST – Étoile du Sahel | 3–2 |
| 12:30 | ES Metlaoui – Club Africain Tunis | 0–1 |
| 12:30 | Esperance Zarzis – Olympique Béja | 1–0 |
| 13:00 | Esteglal Khuzestan – Nassaji Mazandaran | 1–1 |
| 13:00 | Shams Azar Qazvin – Aluminium Arak | 2–2 |
| 13:00 | Esteghlal FC Tehran – Sepahan | 2–0 |
| 13:00 | Shams Azar Qazvin – Aluminium Arak | 1–2 |
| 12:45 | Academia Cantolao – Pirata FC | 1–1 |
| 15:00 | Cesar Vallejo – Club Deportivo Llacuabamba | 2–0 |
| 17:15 | Unión Comercio – Carlos A. Mannucci | 0–0 |
| 11:30 | Fundación Amigos por el Deporte – Sol de Mayo | 2–0 |
| 15:00 | Germinal – San Martín Mendoza | 0–0 |
| 15:00 | Guillermo Brown – Santamarina Tandil | 1–0 |
| 15:00 | Deportivo Rincón – Juventud Unida San Luis | 1–0 |
| 15:00 | Atlético Escobar – Gimnasia de Concepcion del Uruguay | 0–2 |
| 15:30 | Defensores Pto. Vilelas – El Linqueño | 0–0 |
| 15:30 | Independiente Chivilcoy – Tucumán Central | 2–0 |
| 15:30 | Cipolletti – Sportivo y Biblioteca Atenas Rio Cuarto | 2–2 |
| 15:30 | Olimpo de Bahia Blanca – Kimberley Mar Del Plata | 1–0 |
| 15:30 | Alvarado – Argentino MM | 1–1 |
| 15:30 | Defensores Belgrano (VR) – CSCyD Gimnasia y Esgrima (Chivilcoy) | 0–1 |
| 16:00 | Boca Unidos – Sportivo Las Parejas | 1–0 |
| 16:00 | San Martín de Formosa – 9 De Julio Rafaela | 2–1 |
| 16:00 | Sarmiento De La Banda – Sportivo Belgrano | 3–0 |
| 16:00 | CA Bartolomé Mitre (Posadas) – Douglas Haig | 0–3 |
| 12:50 | Hajer – Jeddah Club | 0–3 |
| 13:15 | Al-Saqer – Damac | 0–0 |
| 15:00 | Al Ula FC – Al Jabalain | 3–1 |
| 17:00 | ASA-AL – Gama | 2–0 |
| 10:00 | Mbeya City – Mashujaa Fc | 2–1 |
| 13:00 | Azam FC – Pamba Jiji FC | 2–1 |
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